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|Flybase description||The gene Unc-89 is referred to in FlyBase by the symbol Dmel\Unc-89 (CG33519, FBgn0053519).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: Rho guanyl-nucleotide exchange factor activity; ATP binding; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development; sarcomere organization.
8 alleles are reported.
The phenotypes of these alleles are annotated with: M band; indirect flight muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Dbl homology (DH) domain; Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Myosin light chain kinase-related; Pleckstrin homology-type; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase-like domain; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages.