Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Nipped-A
Flybase description The gene Nipped-A is referred to in FlyBase by the symbol Dmel\Nipped-A (CG33554, FBgn0053554).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -41.398 -27.2942 -40.733787 -41.3932 -49.282205 -38.4892 -46.79147 -40.389518
    Affimetrix absolute value 3.041 2.856 2.854 3.053 3.154 3.297 3.015 2.943
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: protein kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of transcription, DNA-dependent; cytokinesis; positive regulation of Notch signaling pathway; wing disc pattern formation; phagocytosis, engulfment.
73 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; ocellus; mesothoracic tergum; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; PIK-related kinase; PIK-related kinase, FAT; PIK-related kinase, FATC; Phosphatidylinositol 3-/4-kinase, catalytic; Protein kinase-like domain; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.