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|Flybase description||The gene Nipped-A is referred to in FlyBase by the symbol Dmel\Nipped-A (CG33554, FBgn0053554).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: protein kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of transcription, DNA-dependent; cytokinesis; positive regulation of Notch signaling pathway; wing disc pattern formation; phagocytosis, engulfment.
73 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; ocellus; mesothoracic tergum; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; PIK-related kinase; PIK-related kinase, FAT; PIK-related kinase, FATC; Phosphatidylinositol 3-/4-kinase, catalytic; Protein kinase-like domain; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.