Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Frq2
Flybase description The gene Frequenin 2 is referred to in FlyBase by the symbol Dmel\Frq2 (CG5907, FBgn0083228).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -47.7206 -37.9878 -44.615726 -48.7702 -69.018691 -53.6835 -45.07763 -44.557692
    Affimetrix absolute value 2.838 2.407 2.761 2.784 2.662 2.816 3.063 2.782
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: calcium ion binding.
There is experimental evidence that it is involved in the biological process: synaptic transmission; regulation of neurotransmitter secretion; neuromuscular junction development.
9 alleles are reported.
The phenotypes of these alleles are annotated with: NMJ bouton; embryonic/larval neuromuscular junction; type I bouton.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain; Recoverin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.