Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pros25
Flybase description The gene Proteasome 25kD subunit is referred to in FlyBase by the symbol Dmel\Pros25 (CG5266, FBgn0086134).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.4115 3.5226 2.655283 3.2609 2.349559 3.0939 2.05419 2.671368
    Affimetrix absolute value 10.541 9.434 9.578 10.073 9.985 10.187 9.568 9.639
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: endopeptidase activity.
There is experimental evidence that it is involved in the biological process: mitotic spindle elongation; cell proliferation; cellular process; mitotic spindle organization.
9 alleles are reported.
The phenotype of these alleles is annotated with: ventral furrow.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Proteasome A-type subunit; Proteasome, alpha-subunit, conserved site; Proteasome, subunit alpha/beta.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.