Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tum
Flybase description The gene tumbleweed is referred to in FlyBase by the symbol Dmel\tum (CG13345, FBgn0086356).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.8422 -14.2898 -14.779631 -20.4944 -18.194373 -18.3617 -28.48473 -18.079443
    Affimetrix absolute value 3.536 3.789 4.312 4.031 4.586 4.469 3.718 4.067
    Affymetric present call in "x" number of chips 0 0 0 0 0 2 0 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: signal transducer activity; diacylglycerol binding; GTPase activator activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: cellular process; biological regulation; system development; cellular component organization or biogenesis; neuron differentiation; regulation of Wnt receptor signaling pathway; cell differentiation; multicellular organismal development; regulation of signal transduction; cell proliferation; cell fate commitment.
40 alleles are reported.
The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; thoracic segment; acellular anatomical structure; organelle; adult; cellular component organization or biogenesis; cytoplasmic part; nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase C-like, phorbol ester/diacylglycerol binding; Rho GTPase activation protein; Rho GTPase-activating protein domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.