Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Orct2
Flybase description The gene Organic cation transporter 2 is referred to in FlyBase by the symbol Dmel\Orct2 (CG13610, FBgn0086365).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.8653 -0.3138 -7.712082 -4.0134 -10.684902 -3.839 -4.67032 -5.255735
    Affimetrix absolute value 5.639 7.642 5.242 6.44 5.353 6.623 6.343 5.894
    Affymetric present call in "x" number of chips 1 3 0 3 1 3 2 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: organic cation transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: positive regulation of cell growth; germ-band shortening; positive regulation of multicellular organism growth.
13 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing; germ band.
It has one annotated transcript and one annotated polypeptide.
Protein features are: General substrate transporter; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.