Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name su(r)
Flybase description The gene suppressor of rudimentary is referred to in FlyBase by the symbol Dmel\su(r) (CG2194, FBgn0086450).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.946 -1.0786 1.501648 -1.3085 0.330036 -1.6009 -3.40574 -0.415977
    Affimetrix absolute value 6.871 7.511 8.742 8.009 8.754 7.893 6.795 8.137
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: dihydropyrimidine dehydrogenase (NADP+) activity.
There is experimental evidence that it is involved in the biological process: 'de novo' pyrimidine base biosynthetic process.
19 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; 4Fe-4S ferredoxin, iron-sulpur binding domain; Aldolase-type TIM barrel; Alpha-helical ferredoxin; Dihydroorotate dehydrogenase, class 1; Dihydroorotate dehydrogenase, class 1/ 2; Dihydroorotate dehydrogenase, conserved site; Fumarate reductase, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed during early larval stages.