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|Flybase description||The gene IκB kinase-like 2 is referred to in FlyBase by the symbol Dmel\ik2 (CG2615, FBgn0086657).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: positive regulation of caspase activity; microtubule bundle formation; neuron remodeling; bristle morphogenesis; regulation of cytoskeleton organization; sensory organ precursor cell division; maintenance of epithelial integrity, open tracheal system; cell morphogenesis; actin filament organization; cell death.
28 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; organ system; adult segment; external compound sense organ; cell part; eo support cell; organelle; humeral trabecule; late extended germ band embryo; integumentary plate.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.