Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gfA
Flybase description The gene giant fibre A is referred to in FlyBase by the symbol Dmel\gfA (CG32538, FBgn0086778).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -52.207 -35.1001 -44.118444 -51.5935 -78.638525 -62.6185 -58.32388 -52.290542
    Affimetrix absolute value 2.712 2.495 2.744 2.711 2.474 2.595 2.69 2.58
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: nicotinic acetylcholine-activated cation-selective channel activity.
There is experimental evidence that it is involved in the biological process: synaptic transmission; regulation of excitatory postsynaptic membrane potential; visual behavior; jump response.
23 alleles are reported.
The phenotype of these alleles is annotated with: giant fiber neuron.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late pupal stages.