Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sls
Flybase description The gene sallimus is referred to in FlyBase by the symbol Dmel\sls (CG1915, FBgn0086906).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1876 -5.3852 -12.073444 -6.9401 -18.655217 -5.4828 -4.46292 -11.018257
    Affimetrix absolute value 7.323 5.269 4.738 5.603 4.7 6.127 6.429 4.907
    Affymetric present call in "x" number of chips 3 3 2 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin binding; structural constituent of muscle.
There is experimental evidence that it is involved in the biological process: myoblast fusion; mitotic chromosome condensation; locomotion; skeletal muscle tissue development; sarcomere organization; muscle attachment; sister chromatid cohesion; mesoderm development.
68 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: multicellular structure; organ system; anatomical structure; organelle; cytoplasmic part; non-connected developing system; adult segment; intracellular organelle; eo support cell; nucleus; intracellular non-membrane-bounded organelle; embryonic labral segment; organ system subdivision; cell cycle.
It has 13 annotated transcripts and 13 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein of unknown function DUF1136; Ribonuclease H-like; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.