Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name AGO2
Flybase description The gene Argonaute 2 is referred to in FlyBase by the symbol Dmel\AGO2 (CG7439, FBgn0087035).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.5774 2.3157 0.621136 1.6781 -0.635172 1.7436 1.30264 0.21924
    Affimetrix absolute value 8.706 8.827 8.474 9.098 8.432 9.353 8.899 8.181
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; endoribonuclease activity; siRNA binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: biological regulation; gene silencing; cellular component organization or biogenesis; localization; programmed cell death; anatomical structure formation involved in morphogenesis; immune system process; pole cell development; embryonic pattern specification; gland morphogenesis; RNA interference; cell death.
39 alleles are reported.
The phenotypes of these alleles are annotated with: pole cell; condensed chromosome; pole bud.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Argonaute/Dicer protein, PAZ; Domain of unknown function DUF1785; Ribonuclease H-like; Stem cell self-renewal protein Piwi.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.