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|Flybase description||The gene Argonaute 2 is referred to in FlyBase by the symbol Dmel\AGO2 (CG7439, FBgn0087035).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; endoribonuclease activity; siRNA binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: biological regulation; gene silencing; cellular component organization or biogenesis; localization; programmed cell death; anatomical structure formation involved in morphogenesis; immune system process; pole cell development; embryonic pattern specification; gland morphogenesis; RNA interference; cell death.
39 alleles are reported.
The phenotypes of these alleles are annotated with: pole cell; condensed chromosome; pole bud.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Argonaute/Dicer protein, PAZ; Domain of unknown function DUF1785; Ribonuclease H-like; Stem cell self-renewal protein Piwi.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.