Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name gish
Flybase description The gene gilgamesh is referred to in FlyBase by the symbol Dmel\gish (CG6963, FBgn0250823).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.5127 -1.5446 -2.065027 -1.2073 -3.446598 -1.7907 -2.15187 -2.802151
    Affimetrix absolute value 6.619 7.01 7.223 8.119 7.063 7.724 7.458 6.913
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: olfactory learning; glial cell migration; protein phosphorylation; Wnt receptor signaling pathway; spermatogenesis.
55 alleles are reported.
The phenotypes of these alleles are annotated with: spermatogonium; eye; trichogen cell; photoreceptor cell; ommatidium.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: Casein kinase 1 gamma C-terminal; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.