Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dUTPase
Flybase description The gene Deoxyuridine triphosphatase is referred to in FlyBase by the symbol Dmel\dUTPase (CG4584, FBgn0250837).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.3031 -3.8857 -3.481417 -2.9111 -2.380022 -1.9651 -12.06405 -2.833454
    Affimetrix absolute value 6.304 5.662 6.403 6.848 7.518 7.614 4.958 6.752
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: dUTP diphosphatase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: dUTP metabolic process.
2 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: DeoxyUTP pyrophosphatase; DeoxyUTP pyrophosphatase, dUTPase subfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, in adult female stages.