Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name bun
Flybase description The gene bunched is referred to in FlyBase by the symbol Dmel\bun (CG42281, FBgn0259176).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.5232 -1.3249 -1.272332 -0.2604 -1.817033 -1.0962 -1.28683 -1.308437
    Affimetrix absolute value 7.095 7.237 7.852 8.466 7.909 8.43 8.187 7.864
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein homodimerization activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; ovarian follicle cell development; programmed cell death; multicellular organism reproduction; positive regulation of biological process; gamete generation; positive regulation of cell proliferation; cellular component organization or biogenesis; localization; regionalization; gland morphogenesis; sensory organ development.
145 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; organ system; external compound sense organ; adult segment; peripheral nervous system; acellular anatomical structure; thoracic segment; histaminergic neuron; epithelial cell; eo support cell.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: TSC-22 / Dip / Bun.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.