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|Flybase description||The gene canoe is referred to in FlyBase by the symbol Dmel\cno (CG42312, FBgn0259212).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: embryonic morphogenesis; dorsal closure; regulation of JNK cascade; epidermis morphogenesis; compound eye development; ommatidial rotation.
54 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; histaminergic neuron; organ system; extended germ band embryo; head mesoderm; cell part; adherens junction; acellular anatomical structure; rhabdomere; primary pigment cell; cell junction.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Dil domain; Dilute; Forkhead-associated (FHA) domain; PDZ/DHR/GLGF; Ras-association; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.