Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name brp
Flybase description The gene bruchpilot is referred to in FlyBase by the symbol Dmel\brp (CG42344, FBgn0259246).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -59.0244 -40.0313 -53.000963 -57.0669 -83.308104 -63.8233 -80.64469 -58.74859
    Affimetrix absolute value 2.534 2.313 2.477 2.559 2.389 2.571 2.223 2.412
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: calcium channel activity.
There is experimental evidence that it is involved in the biological process: synaptic transmission; neuromuscular synaptic transmission; regulation of synaptic plasticity; neurotransmitter secretion; adult locomotory behavior; maintenance of presynaptic active zone structure; short-term memory; anesthesia-resistant memory.
25 alleles are reported.
The phenotypes of these alleles are annotated with: t-bar; embryonic/larval neuromuscular junction; mesothoracic tergum.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: CAZ complex, RIM-binding protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.