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|Flybase description||The gene Nucleolar protein at 60B is referred to in FlyBase by the symbol Dmel\Nop60B (CG3333, FBgn0259937).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pseudouridylate synthase activity.
There is experimental evidence that it is involved in the biological process: wing disc development; ribosome biogenesis; germ cell development; rRNA processing; pseudouridine synthesis; neurogenesis.
21 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; adult segment; organ system subdivision; multicellular structure; thoracic segment; sense organ; eo support cell; adult; imaginal precursor; portion of tissue.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Dyskerin-like; PUA-like domain; Pseudouridine synthase II; Pseudouridine synthase, catalytic domain; Pseudouridine synthase-related; Pseudouridine synthase/archaeosine transglycosylase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.