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|Flybase description||The gene kuzbanian is referred to in FlyBase by the symbol Dmel\kuz (CG7147, FBgn0259984).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: metalloendopeptidase activity.
There is experimental evidence that it is involved in the biological process: heart morphogenesis; Notch receptor processing; border follicle cell migration; glial cell migration; skeletal muscle tissue development; muscle tissue development; pericardial cell differentiation; cardiac cell differentiation; lymph gland development; phagocytosis, engulfment.
84 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system subdivision; organ system; adult segment; thoracic segment; external compound sense organ; sense organ; multicellular structure; peripheral nervous system; embryonic dorsal vessel; embryonic pericardial cell; non-connected developing system; imaginal precursor.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Blood coagulation inhibitor, Disintegrin; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.