Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Dys
Flybase description The gene Dystrophin is referred to in FlyBase by the symbol Dmel\Dys (CG34157, FBgn0260003).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -47.0467 -23.0848 -30.002886 -27.4173 -41.067881 -56.593 -44.55616 -35.893457
    Affimetrix absolute value 2.857 3.111 3.282 3.628 3.418 2.745 3.093 3.09
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: WW domain binding.
There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; regulation of neurotransmitter secretion; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; regulation of short-term neuronal synaptic plasticity; muscle cell homeostasis; establishment of cell polarity.
52 alleles are reported.
The phenotypes of these alleles are annotated with: posterior crossvein; t-bar; presynaptic active zone; oocyte; terminal button; neuromuscular junction; eye photoreceptor cell; indirect flight muscle.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Actinin-type, actin-binding, conserved site; Calponin homology domain; EF-hand domain, type 1; EF-hand domain, type 2; EF-hand-like domain; Spectrin repeat; Spectrin/alpha-actinin; WW/Rsp5/WWP; Zinc finger, ZZ-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-18 embryonic stages, during late pupal stages.