Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name spdo
Flybase description The gene sanpodo is referred to in FlyBase by the symbol Dmel\spdo (CG31020, FBgn0260440).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.3827 -21.2555 -22.579011 -33.4749 -27.511088 -27.6581 -46.08073 -20.170492
    Affimetrix absolute value 3.216 3.253 3.695 3.326 3.981 3.79 3.051 3.927
    Affymetric present call in "x" number of chips 0 3 2 1 1 2 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Notch binding; protein binding.
There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; heart morphogenesis; sensory organ development; Notch signaling pathway; sensory organ precursor cell division; asymmetric cell division.
21 alleles are reported.
The phenotypes of these alleles are annotated with 50 unique terms, many of which group under: organ system; organ system subdivision; hypodermal muscle of larval abdomen; abdominal dorsal bipolar neuron dbp; embryonic/larval neuron; peripheral nervous system; larval abdominal segment; non-connected developing system; adult segment; sense organ.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.