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|Flybase description||The gene metabotropic GABA-B receptor subtype 1 is referred to in FlyBase by the symbol Dmel\GABA-B-R1 (CG15274, FBgn0260446).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GABA-B receptor activity.
Based on sequence similarity, it is predicted to be involved in the biological process: G-protein coupled receptor protein signaling pathway.
9 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Extracellular ligand-binding receptor; GPCR, family 3, C-terminal; GPCR, family 3, gamma-aminobutyric acid receptor, type B; GPCR, family 3, gamma-aminobutyric acid receptor, type B1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.