Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name th
Flybase description The gene thread is referred to in FlyBase by the symbol Dmel\th (CG12284, FBgn0260635).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.8334 4.4079 3.514076 9.6991 2.435012 5.5245 2.41633 4.3806
    Affimetrix absolute value 10.339 9.747 9.99 11.663 10.041 11.019 9.819 10.349
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: enzyme binding; protein binding; NEDD8 ligase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; sensory organ development; regulation of apoptosis; system development; cellular process; cellular component organization or biogenesis; multicellular organismal development; programmed cell death; localization; post-embryonic organ morphogenesis.
175 alleles are reported.
The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; portion of tissue; external compound sense organ; adult segment; imaginal precursor; non-connected developing system; cell part; cytoplasmic part; embryonic procephalic segment; anatomical structure; embryonic mandibular segment; synapse.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Baculoviral inhibition of apoptosis protein repeat; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.