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|Flybase description||The gene thread is referred to in FlyBase by the symbol Dmel\th (CG12284, FBgn0260635).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: enzyme binding; protein binding; NEDD8 ligase activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: biological regulation; sensory organ development; regulation of apoptosis; system development; cellular process; cellular component organization or biogenesis; multicellular organismal development; programmed cell death; localization; post-embryonic organ morphogenesis.
175 alleles are reported.
The phenotypes of these alleles are annotated with 28 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; portion of tissue; external compound sense organ; adult segment; imaginal precursor; non-connected developing system; cell part; cytoplasmic part; embryonic procephalic segment; anatomical structure; embryonic mandibular segment; synapse.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Baculoviral inhibition of apoptosis protein repeat; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.