Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name mxc
Flybase description The gene multi sex combs is referred to in FlyBase by the symbol Dmel\mxc (CG12124, FBgn0260789).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.6284 -8.4088 -16.453326 -13.1641 -19.9695 -16.6294 -17.63008 -14.528991
    Affimetrix absolute value 4.201 4.57 4.148 4.695 4.448 4.517 4.428 4.414
    Affymetric present call in "x" number of chips 2 2 1 0 0 2 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: lateral inhibition; hemocyte differentiation; hemocyte proliferation; neurogenesis.
14 alleles are reported.
The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: organ system; adult segment; organ system subdivision; imaginal precursor; embryonic/larval hemocoel; thoracic segment; eo support cell; male accessory gland; embryonic/larval fat body; cell part; acellular anatomical structure; prothoracic leg disc; external compound sense organ; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AT hook, DNA-binding motif; LisH dimerisation motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.