|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene G protein-coupled receptor kinase 1 is referred to in FlyBase by the symbol Dmel\Gprk1 (CG40129, FBgn0260798).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: G-protein-coupled receptor binding; ATP binding; phosphatidylinositol binding; rhodopsin kinase activity.
There is experimental evidence that it is involved in the biological process: protein phosphorylation; imaginal disc-derived wing vein specification; phototransduction, visible light; metarhodopsin inactivation.
7 alleles are reported.
The phenotype of these alleles is annotated with: wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; GPCR kinase; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Regulator of G protein signalling; Regulator of G protein signalling superfamily; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period.