Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dnr1
Flybase description The gene defense repressor 1 is referred to in FlyBase by the symbol Dmel\dnr1 (CG12489, FBgn0260866).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.3184 -5.7459 -3.295796 -2.8243 -5.711284 -3.2879 -7.50348 -3.625119
    Affimetrix absolute value 6.684 5.125 6.468 6.937 6.287 6.872 5.757 6.403
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding.
There is experimental evidence that it is involved in the biological process: negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; immune response.
20 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Band 4.
1 domain; FERM central domain; FERM domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; Pleckstrin homology-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.