Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name stj
Flybase description The gene straightjacket is referred to in FlyBase by the symbol Dmel\stj (CG12295, FBgn0261041).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -61.2233 -38.036 -54.29092 -62.2957 -83.382937 -71.4076 -72.04673 -61.074357
    Affimetrix absolute value 2.483 2.374 2.421 2.446 2.384 2.404 2.41 2.328
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: voltage-gated calcium channel activity.
There is experimental evidence that it is involved in the biological process: negative regulation of synaptic growth at neuromuscular junction; neuromuscular synaptic transmission; sensory perception of pain; synaptic vesicle fusion to presynaptic membrane.
26 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval neuromuscular junction; embryonic/larval somatic muscle.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Cache; VWA N-terminal; von Willebrand factor, type A.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.