Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Prp19
Flybase description The gene Prp19 is referred to in FlyBase by the symbol Dmel\Prp19 (CG5519, FBgn0261119).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8943 -1.6244 -2.420231 -2.0799 -3.171405 -2.4289 -2.99086 -3.177395
    Affimetrix absolute value 6.885 6.924 6.935 7.347 7.105 7.298 6.981 6.669
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: ubiquitin-protein ligase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: nuclear mRNA splicing, via spliceosome.
5 alleles are reported.
The phenotype of these alleles is annotated with: crystal cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: G-protein beta WD-40 repeat; Pre-mRNA-splicing factor 19; Quinonprotein alcohol dehydrogenase-like; U box domain; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.