Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hr39
Flybase description The gene Hormone receptor-like in 39 is referred to in FlyBase by the symbol Dmel\Hr39 (CG8676, FBgn0261239).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -14.1011 -4.6502 -6.942823 -9.5477 -10.921024 -8.3396 -7.05867 -8.728883
    Affimetrix absolute value 4.685 5.417 5.41 5.14 5.329 5.503 5.737 5.22
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ligand-dependent nuclear receptor activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; activation of caspase activity; spermathecum morphogenesis; regulation of gene silencing; ecdysone-mediated induction of salivary gland cell autophagic cell death.
39 alleles are reported.
The phenotypes of these alleles are annotated with: spermathecum; eye; trichogen cell; ovary; macrochaeta; female accessory gland; wing.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Steroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages.