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|Flybase description||The gene Megalin is referred to in FlyBase by the symbol Dmel\Megalin (CG42611, FBgn0261260).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||There is not condition-dependent expression data available for this gene.|
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: low-density lipoprotein receptor activity.
The biological processes in which it is involved are not known.
22 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: EGF calcium-binding; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Growth factor, receptor; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.