Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name plx
Flybase description The gene pollux is referred to in FlyBase by the symbol Dmel\plx (CG42612, FBgn0261261).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.1055 -27.5568 -34.309306 -43.4599 -55.3813 -48.6766 -53.37594 -29.340043
    Affimetrix absolute value 2.95 2.863 3.101 2.951 2.979 2.964 2.814 3.375
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: integrin binding.
There is experimental evidence that it is involved in the biological process: cell adhesion mediated by integrin.
14 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval tracheal system.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Phosphotyrosine interaction domain; Pleckstrin homology-type; Protein of unknown function DUF3350; Rab-GAP/TBC domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.