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|Flybase description||The gene grapes is referred to in FlyBase by the symbol Dmel\grp (CG17161, FBgn0261278).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein kinase activity; protein serine/threonine kinase activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; centrosome separation; cell cycle arrest; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of syncytial blastoderm mitotic cell cycle; spindle assembly; cell cycle; DNA damage checkpoint.
97 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: multicellular structure; anatomical structure; cleavage stage embryo; sense organ; eo support cell; syncytial blastoderm embryo; organelle; cell cluster organ; blastoderm embryo; cell part; intracellular organelle part.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.