Flygut: an atlas of the Drosophila adult midgut

Mouche Logo_lab_lemaitre Bbcf_logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression

What is Flygut?

An interactive Database that aims to provide a comprehensive atlas of the Drosophila melanogaster adult midgut. You will find an exhaustive description of the different regions of the adult midgut, including the coordinates of each region, their anatomical and histological characteristics, as well as gut- and region-specific gene expression data. This resource is associated to the publication:
Morphological and molecular characterization of adult midgut compartmentalization in Drosophila. Cell reports. 2013. Nicolas Buchon*, Dani Osman*, Fabrice P.A. David, Jean-philippe Boquete, Bart Deplancke and Bruno Lemaitre*. [Pubmed]

For cell-specific (Intestinal Stem Cells, Enteroblasts, Enterocytes, Enteroendocrine cells, and Visceral Muscles) and region-specific transcriptomic data of the Drosophila midgut, please visit Flygut-seq.

In Flygut, you will find:
  • Overview of gut regions: a summary describing the organization of the Drosophila adult midgut in several regions with different identities.
  • Anatomy: a morphometric description of the Drosophila adult gut regions and their boundaries in 2D and 3D.
  • Histology: a histological description of the Drosophila adult gut regions and their boundaries in 2D and 3D.
  • Transgene expression mapping: a description of the expression patterns of 210 enhancer-trap lines along the Drosophila adult digestive tract.
  • Gene expression: A transcriptome analysis of the main Drosophila adult gut regions and an analysis of Gene Ontology enrichment per region.