Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Ace
Flybase description The gene Acetylcholine esterase is referred to in FlyBase by the symbol Dmel\Ace (CG17907, FBgn0000024).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.9933 3.7162 -3.212153 -22.9295 -9.097471 -11.0243 -48.82692 -4.11049
    Affimetrix absolute value 7.436 9.489 6.552 3.883 5.588 5.119 2.947 6.254
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 1 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cholinesterase activity; protein homodimerization activity; acetylcholinesterase activity.
There is experimental evidence that it is involved in the biological process: phototaxis; synaptic transmission; choline catabolic process; acetylcholine catabolic process.
73 alleles are reported.
The phenotypes of these alleles are annotated with: aCC neuron; RP2 neuron; NMJ bouton.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Acetylcholinesterase, insect; Carboxylesterase type B, active site; Carboxylesterase type B, conserved site; Carboxylesterase, type B; Cholinesterase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.
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