Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name nAcRalpha-96Aa
Flybase description The gene nicotinic Acetylcholine Receptor alpha 96Aa is referred to in FlyBase by the symbol Dmel\nAcRα-96Aa (CG5610, FBgn0000036).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.117 -13.6561 -15.045924 -17.6198 -23.544664 -22.0324 -20.49938 -18.983658
    Affimetrix absolute value 4.311 3.894 4.28 4.249 4.203 4.107 4.196 4.031
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 2 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: nicotinic acetylcholine-activated cation-selective channel activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
9 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
.