Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Act5C
Flybase description The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.2557 39.3869 36.150343 34.6377 24.261894 33.801 16.26291 33.823536
    Affimetrix absolute value 11.014 12.906 13.335 13.498 13.35 13.638 12.545 13.278
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton.
There is experimental evidence that it is involved in the biological process: sperm individualization; inter-male aggressive behavior; cytokinesis; mushroom body development; maintenance of protein location in cell; phagocytosis, engulfment.
64 alleles are reported.
The phenotypes of these alleles are annotated with: germline cyst; trichome; eye; trichogen cell; border follicle cell; arista; macrochaeta; anterior crossvein; mushroom body alpha-lobe; mushroom body alpha'-lobe.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Actin, conserved site; Actin-like; Actin/actin-like conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.
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