Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Act57B
Flybase description The gene Actin 57B is referred to in FlyBase by the symbol Dmel\Act57B (CG10067, FBgn0000044).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 43.2183 27.6216 14.880098 17.0355 9.424819 18.3509 36.25608 22.889359
    Affimetrix absolute value 13.805 12.305 11.949 12.456 11.924 12.736 13.727 12.632
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton.
There is experimental evidence that it is involved in the biological process: positive regulation of NFAT protein import into nucleus; cytokinesis.
7 alleles are reported.
The phenotype of these alleles is annotated with: germline cyst.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Actin, conserved site; Actin-like; Actin/actin-like conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages.
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