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Gene name | ade3 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene adenosine 3 is referred to in FlyBase by the symbol Dmel\ade3 (CG31628, FBgn0000053). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process: 'de novo' IMP biosynthetic process. 19 alleles are reported. The phenotypes of these alleles are annotated with: ventral row; tarsal segment; dorsal row; wing; wing vein; macrochaeta; pigment cell; trichome of the posterior wing margin. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AIR synthase-related protein; AIR synthase-related protein, C-terminal; ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Formyl transferase, N-terminal; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; Phosphoribosylglycinamide formyltransferase, active site; Phosphoribosylglycinamide synthetase; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C-domain; Phosphoribosylglycinamide synthetase, N-terminal; Phosphoribosylglycinamide synthetase, conserved site; Pre-ATP-grasp fold; PreATP-grasp-like fold; PurM, N-terminal-like; Rudiment single hybrid motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages. . |