Flygut: an atlas of the Drosophila adult midgut

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Gene name ade3
Flybase description The gene adenosine 3 is referred to in FlyBase by the symbol Dmel\ade3 (CG31628, FBgn0000053).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.3785 0.3334 -1.355364 -1.5185 -1.843135 -1.6947 -1.50789 -1.698669
    Affimetrix absolute value 7.946 7.619 7.739 7.807 7.882 7.819 7.985 7.516
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: 'de novo' IMP biosynthetic process.
19 alleles are reported.
The phenotypes of these alleles are annotated with: ventral row; tarsal segment; dorsal row; wing; wing vein; macrochaeta; pigment cell; trichome of the posterior wing margin.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: AIR synthase-related protein; AIR synthase-related protein, C-terminal; ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Formyl transferase, N-terminal; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; Phosphoribosylglycinamide formyltransferase, active site; Phosphoribosylglycinamide synthetase; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C-domain; Phosphoribosylglycinamide synthetase, N-terminal; Phosphoribosylglycinamide synthetase, conserved site; Pre-ATP-grasp fold; PreATP-grasp-like fold; PurM, N-terminal-like; Rudiment single hybrid motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed during late larval stages, during early pupal stages.
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