Flygut: an atlas of the Drosophila adult midgut

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Gene name Adh
Flybase description The gene Alcohol dehydrogenase is referred to in FlyBase by the symbol Dmel\Adh (CG3481, FBgn0000055).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 50.0292 44.4143 11.503034 1.9902 3.336424 13.6774 27.46258 19.755966
    Affimetrix absolute value 14.04 13.067 11.619 9.347 10.349 12.26 13.308 12.471
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein homodimerization activity; alcohol dehydrogenase (NAD) activity; acetaldehyde dehydrogenase (acetylating) activity.
There is experimental evidence that it is involved in the biological process: alcohol catabolic process; alcohol metabolic process; ethanol oxidation; behavioral response to ethanol; acetaldehyde metabolic process; ethanol metabolic process.
587 alleles are reported.
No phenotypic data is available.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Alcohol dehydrogenase, Drosophila-type; Alcohol dehydrogenase, insect-type; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of low expression.
Peak expression observed at stages throughout the larval period, in adult male stages.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.
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