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Gene name | al | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene aristaless is referred to in FlyBase by the symbol Dmel\al (CG3935, FBgn0000061). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process: bristle development; antennal morphogenesis; positive regulation of Notch signaling pathway; leg disc development; imaginal disc-derived leg morphogenesis; elongation of arista core; negative regulation of transcription, DNA-dependent. 28 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; appendage segment; external compound sense organ; antennal segment; compound cell cluster organ; unguis; integumentary plate; mesothoracic preepisternum. It has one annotated transcript and one annotated polypeptide. Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Paired-like homeodomain protein, OAR. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages. . |