Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name aop
Flybase description The gene anterior open is referred to in FlyBase by the symbol Dmel\aop (CG3166, FBgn0000097).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.822 0.4147 -1.486337 -1.6393 -3.469507 -1.8259 -2.98589 -2.555388
    Affimetrix absolute value 7.565 7.72 7.637 7.695 7.037 7.698 7.004 7.014
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 16 unique biological process terms, many of which group under: anatomical structure development; biological regulation; sensory organ development; cellular component organization or biogenesis; organ development; localization; regulation of developmental process; cellular process involved in reproduction; cell fate determination; muscle organ development; muscle cell differentiation; positive regulation of programmed cell death; delamination; regulation of multicellular organismal development.
100 alleles are reported.
The phenotypes of these alleles are annotated with 56 unique terms, many of which group under: organ system subdivision; external compound sense organ; peripheral nervous system; organ system; adult segment; nervous system; non-connected developing system; hemocyte; presumptive embryonic/larval nervous system; late extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ets; Sterile alpha motif homology; Sterile alpha motif-type; Sterile alpha motif/pointed; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages.
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