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Gene name | Appl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene β amyloid protein precursor-like is referred to in FlyBase by the symbol Dmel\Appl (CG7727, FBgn0000108). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: neuron projection morphogenesis; long-term memory; response to axon injury; peripheral nervous system development; synapse organization. 28 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; adult segment; nervous system; adult mesothoracic segment; peripheral nervous system; sensillum; organ system; eo support cell; external compound sense organ; wing pouch. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Amyloidogenic glycoprotein, copper-binding; Amyloidogenic glycoprotein, extracellular; Amyloidogenic glycoprotein, extracellular domain conserved site; Amyloidogenic glycoprotein, heparin-binding; Amyloidogenic glycoprotein, intracellular domain, conserved site; Beta-amyloid precursor protein C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages. . |