Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name awd
Flybase description The gene abnormal wing discs is referred to in FlyBase by the symbol Dmel\awd (CG2210, FBgn0000150).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 11.2726 17.9108 13.808777 10.8393 9.978088 10.5768 10.57714 13.502957
    Affimetrix absolute value 11.902 11.77 11.962 11.824 12.076 11.959 11.951 11.987
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: microtubule binding; GTP binding; nucleoside diphosphate kinase activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: anatomical structure development; macromolecule modification; protein modification process; phosphorus metabolic process; cellular macromolecule metabolic process; cellular component organization or biogenesis; open tracheal system development; primary metabolic process; small molecule biosynthetic process; multicellular organismal process; microtubule-based process; establishment or maintenance of polarity of follicular epithelium; biological regulation.
62 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval dorsal trunk; follicle cell; embryonic/larval tracheal system; presumptive embryonic/larval tracheal system; dorsal group branch precursor; egg chamber; dorsal trunk primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nucleoside diphosphate kinase; Nucleoside diphosphate kinase, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.
Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.
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