Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name bcd
Flybase description The gene bicoid is referred to in FlyBase by the symbol Dmel\bcd (CG1034, FBgn0000166).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -25.4502 -17.8253 -24.929529 -30.6793 -41.469506 -39.9349 -36.23931 -25.424694
    Affimetrix absolute value 3.741 3.483 3.545 3.45 3.39 3.243 3.373 3.595
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; translation repressor activity; protein binding; mRNA 3'-UTR binding; sequence-specific enhancer binding RNA polymerase II transcription factor activity.
There is experimental evidence that it is involved in the biological process: oogenesis; segment polarity determination; positive regulation of transcription from RNA polymerase II promoter; negative regulation of translation; anterior region determination.
421 alleles are reported.
The phenotypes of these alleles are annotated with 51 unique terms, many of which group under: embryonic segment; embryonic abdomen; organ system; abdominal ventral denticle belt; cephalopharyngeal skeleton; thoracic segment; organ system subdivision; pharyngeal sclerite; spiracle; extended germ band embryo.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.
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