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Gene name | ben | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene bendless is referred to in FlyBase by the symbol Dmel\ben (CG18319, FBgn0000173). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process: jump response; response to anesthetic; flight behavior; axonogenesis; axon target recognition; photoreceptor cell morphogenesis; grooming behavior. 25 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system subdivision; external compound sense organ; peripheral nervous system; adult segment; nervous system; adult mesothoracic segment; multi-cell-component structure; indirect flight muscle; synaptic neuropil subdomain; rhabdomere R7. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during early pupal stages. . |