Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name bi
Flybase description The gene bifid is referred to in FlyBase by the symbol Dmel\bi (CG3578, FBgn0000179).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -42.7366 -26.1119 -31.753564 -36.8074 -44.993427 -47.5608 -36.71451 -34.668728
    Affimetrix absolute value 3.006 2.929 3.216 3.187 3.279 2.99 3.355 3.147
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: wing disc morphogenesis; wing disc anterior/posterior pattern formation; imaginal disc-derived wing morphogenesis; organ growth; compound eye morphogenesis.
71 alleles are reported.
The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; lobula complex; external compound sense organ; thoracic segment; dorsal thoracic disc; multi-cell-component structure; antennal segment; wing pouch.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Optomotor-blind protein, N-terminal; Transcription factor, T-box; Transcription factor, T-box, conserved site; p53-like transcription factor, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages.
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