Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name brm
Flybase description The gene brahma is referred to in FlyBase by the symbol Dmel\brm (CG5942, FBgn0000212).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.4235 -1.1979 -3.189069 -2.012 -5.174135 -2.0453 -1.87274 -4.11146
    Affimetrix absolute value 6.645 7.36 6.586 7.397 6.5 7.53 7.686 6.387
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; post-embryonic appendage morphogenesis; post-embryonic organ morphogenesis; biological regulation; cell projection organization; dendrite morphogenesis; muscle organ development; organ morphogenesis; localization; positive regulation of response to stimulus.
57 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; eo support cell; external compound sense organ; cell projection; sensillum; neuron projection; peripheral nervous system; embryonic/larval hemocoel; axon; adult external prothorax.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: BRK domain; Bromodomain; Bromodomain, conserved site; DEAD-like helicase; Glutamine-Leucine-Glutamine, QLQ; HAS subgroup; HSA; Helicase, C-terminal; Helicase/SANT-associated, DNA binding; SNF2-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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