Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Cam
Flybase description The gene Calmodulin is referred to in FlyBase by the symbol Dmel\Cam (CG8472, FBgn0000253).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.0974 7.8858 7.211714 6.9408 5.190644 8.4559 4.2885 6.747398
    Affimetrix absolute value 10.021 10.583 10.979 11.179 11.097 11.64 10.648 10.889
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: calmodulin binding; myosin heavy chain binding; myosin VI head/neck binding.
There is experimental evidence that it is involved in the biological process: rhodopsin mediated signaling pathway; protein phosphorylation; positive regulation of NFAT protein import into nucleus; mitotic spindle organization; centriole replication; regulation of light-activated channel activity; kinetochore organization; metarhodopsin inactivation; lateral inhibition.
60 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; pupa; mesothoracic tergum; longitudinal muscle; ommatidium; wing vein; adult head; chaeta; pupal cuticle.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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