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Gene name | Cam | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Calmodulin is referred to in FlyBase by the symbol Dmel\Cam (CG8472, FBgn0000253). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: calmodulin binding; myosin heavy chain binding; myosin VI head/neck binding. There is experimental evidence that it is involved in the biological process: rhodopsin mediated signaling pathway; protein phosphorylation; positive regulation of NFAT protein import into nucleus; mitotic spindle organization; centriole replication; regulation of light-activated channel activity; kinetochore organization; metarhodopsin inactivation; lateral inhibition. 60 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor; pupa; mesothoracic tergum; longitudinal muscle; ommatidium; wing vein; adult head; chaeta; pupal cuticle. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |