Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cni
Flybase description The gene cornichon is referred to in FlyBase by the symbol Dmel\cni (CG5855, FBgn0000339).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.28 3.872 4.764242 3.4312 3.96094 3.3763 2.3698 4.152507
    Affimetrix absolute value 9.597 9.565 10.428 10.162 10.742 10.313 9.778 10.293
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: blastoderm segmentation; establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification; bicoid mRNA localization; intracellular mRNA localization; dorsal/ventral pattern formation; ER to Golgi vesicle-mediated transport; vesicle-mediated transport; anterior/posterior pattern formation; dorsal appendage formation; pole plasm oskar mRNA localization.
12 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; organ system; egg; external compound sense organ; female germline cyst; adult segment; sensillum; adult mesothoracic segment; primordium; cell part.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Cornichon.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.
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