Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name crm
Flybase description The gene cramped is referred to in FlyBase by the symbol Dmel\crm (CG2714, FBgn0000376).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.4631 -8.1032 -11.443056 -11.6881 -19.051474 -14.7936 -11.63474 -15.138259
    Affimetrix absolute value 4.89 4.601 4.685 4.856 4.526 4.705 5.047 4.352
    Affymetric present call in "x" number of chips 3 3 2 3 1 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: segment specification.
35 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system subdivision; antennal segment; appendage segment; somatic cell; external compound sense organ; adult mesothoracic segment; thoracic segment; organ system; prothoracic leg; compound cell cluster organ; pigment cell; metatarsus.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SANT domain, DNA binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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