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Gene name | cup | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene cup is referred to in FlyBase by the symbol Dmel\cup (CG11181, FBgn0000392). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; RNA binding; translation regulator activity. There is experimental evidence that it is involved in the biological process: meiotic chromosome segregation; intracellular mRNA localization; regulation of pole plasm oskar mRNA localization; dorsal/ventral pattern formation; female meiosis; oogenesis; negative regulation of oskar mRNA translation; regulation of translation; negative regulation of translation; ovarian follicle cell migration. 67 alleles are reported. The phenotypes of these alleles are annotated with: karyosome; chorion; egg chamber; dorsal appendage; ovary; cleavage nucleus. It has one annotated transcript and one annotated polypeptide. Protein features are: Eukaryotic translation initiation factor 4E transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. . |