Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name cup
Flybase description The gene cup is referred to in FlyBase by the symbol Dmel\cup (CG11181, FBgn0000392).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.3321 1.2151 1.400648 1.3104 -1.095894 1.093 -1.19469 1.144868
    Affimetrix absolute value 8.408 7.887 8.656 8.775 8.626 8.689 8.295 8.431
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; RNA binding; translation regulator activity.
There is experimental evidence that it is involved in the biological process: meiotic chromosome segregation; intracellular mRNA localization; regulation of pole plasm oskar mRNA localization; dorsal/ventral pattern formation; female meiosis; oogenesis; negative regulation of oskar mRNA translation; regulation of translation; negative regulation of translation; ovarian follicle cell migration.
67 alleles are reported.
The phenotypes of these alleles are annotated with: karyosome; chorion; egg chamber; dorsal appendage; ovary; cleavage nucleus.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Eukaryotic translation initiation factor 4E transporter.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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